---
title: "High blood sugar: symptoms, ketones and the 300 mg/dL line"
description: "Thirst, frequent urination, blurry vision: the signs of high blood sugar, the CDC's 250 and 300 mg/dL lines, ketones, and when to go to the ER."
canonical: https://glucosebench.com/high-blood-sugar
alternate_html: https://glucosebench.com/high-blood-sugar
language: en-US
last_updated: 2026-09-27
type: guia
---
# High blood sugar (hyperglycemia): the signs, and the readings that can't wait

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3.  High blood sugar (hyperglycemia): the signs, and the readings that can't wait

Most high readings are a nudge to look at food, activity, illness or a missed dose. A few are an emergency, and the CDC draws that line with numbers.

By **GlucoseBench editorial team**Updated September 27, 2026

![High blood sugar (hyperglycemia): the signs, and the readings that can't wait](https://glucosebench.com/img/guia-high-blood-sugar-640.webp)

Short answer

Hyperglycemia means high blood glucose; for most people with diabetes, the NIDDK says blood sugar is too high "when it is above 180 mg/dL." The usual signs are feeling thirsty, feeling tired or weak, headaches, urinating often and blurred vision. If you have diabetes and you're sick or your blood sugar is 250 mg/dL or above, the CDC says to check your blood sugar every 4 to 6 hours and check your urine for ketones. Go to the emergency room or call 911 right away if your blood sugar stays at 300 mg/dL or above, your breath smells fruity, you're vomiting and can't keep food or drinks down, you're having trouble breathing, or you have multiple signs and symptoms of DKA. Supplements have no place in that plan; the CDC's own line is "Take medicines as prescribed, even if you feel fine."

## Readings that change what you do

The number thresholds are written for people who already have diabetes and check at home. The CDC's emergency list applies to everyone, diagnosed or not: go to the emergency room or call 911 right away for fruity-smelling breath, vomiting with no way to keep food or drinks down, trouble breathing, a blood sugar that stays at 300 mg/dL or above, or several signs and symptoms of DKA at once. If you've never been diagnosed and see high readings without those signs, see a health care provider to find out why; the CDC notes that DKA is sometimes the first sign of diabetes.

Reading

What the source says to do

Source

Above 180 mg/dL, often

Talk with your health care team; your meal plan, activity or medicines may need a change

NIDDK

250 mg/dL or above, or you're sick

Check your blood sugar every 4 to 6 hours and check your urine for ketones

CDC

Any symptom of DKA

"You should also test for ketones if you have any of the symptoms of DKA."

CDC

Very high blood glucose or DKA symptoms, and ketones come back moderate or high (or you have no ketone test)

Check ketones every 4 to 6 hours "when your blood glucose is very high or when you are having these symptoms." If moderate or high, or with no test: "contact your health care provider right away or get emergency medical help"

MedlinePlus

Stays at 300 mg/dL or above

Go to the emergency room or call 911 right away

CDC

Several signs of DKA, fruity breath, vomiting with nothing staying down, or trouble breathing

Go to the emergency room or call 911 right away, with or without a diabetes diagnosis

CDC

Sources: NIDDK, "Managing Diabetes" (last reviewed October 2023); CDC, "Diabetic Ketoacidosis" (May 15, 2024); MedlinePlus, "Hyperglycemia" (updated May 10, 2024). All read on September 27, 2026. On high ketones, the CDC is shorter still: "Call 911 or go to the emergency room right away."

## What running high feels like

### The everyday signs

MedlinePlus lists feeling thirsty, feeling tired or weak, headaches, urinating often and blurred vision. The NIDDK's list is the same idea: tired, thirsty, blurry vision, urinating too often.

### When it stays high

"In people with diabetes, long-term hyperglycemia can lead to serious health problems," says MedlinePlus. The NIDDK adds that very high blood glucose "may lead to confusion or fainting."

### Signs of DKA

The CDC's early signs of diabetic ketoacidosis are being very thirsty and urinating a lot more than usual. "If untreated, more severe symptoms can appear quickly": fast, deep breathing, dry skin and mouth, a flushed face, fruity-smelling breath, headache, muscle aches, deep tiredness, nausea, vomiting and stomach pain. It can be the first sign of diabetes in someone never diagnosed.

### Often, nothing

"Prediabetes and type 2 diabetes often don't have any symptoms," the CDC notes. Feeling fine doesn't tell you your number.

## What pushes blood sugar up

MedlinePlus puts it plainly: with diabetes, you can get hyperglycemia "if you eat too much food or the wrong foods, don't take your medicines correctly, or don't get physical activity," and also when you're stressed or sick. For DKA, the CDC puts illness and missed insulin (skipped shots, a clogged pump, the wrong dose) at the top of the list.

Without diabetes, it's less common. MedlinePlus names problems with the pancreas or adrenal glands, certain medicines and severe illnesses, and says anyone without diabetes who has the symptoms should see a provider to find the cause.

## What to do with a high reading

1.  ### Write it down
    
    The NIDDK asks you to record the date and time, the result, and what you ate or did that day, and to bring it to your health care team.
    
2.  ### Look for the reason
    
    Too much food, less activity, a missed or wrong dose, stress, an illness. Those are the causes MedlinePlus and the CDC name.
    
3.  ### If you are sick, check more often
    
    The CDC: "Check your blood sugar often, especially if you're sick." At 250 mg/dL or above, that means every 4 to 6 hours, plus a ketone check.
    
4.  ### Tell your team if it keeps happening
    
    "Talk with your health care team if you often have high blood glucose levels," says the NIDDK. The fix may be a change in your meal plan, activity or medicines, and that change is theirs to make with you.
    

## Sales pages vs. public health advice

Four products reviewed on this site are sold with lines that point the opposite way from the CDC and the NIH. We don't recommend any of them.

What the sales page says

Product

What the official source says

"You cannot control diabetes with medications or insulin."

Blood Sugar Blaster

CDC: "Take medicines as prescribed, even if you feel fine." Missed insulin shots are one of the two most common causes of DKA.

"No more blood sugar monitoring, test strips, insulin injections"

Blood Sugar Blaster

CDC: "Check your blood sugar often, especially if you're sick."

"Dealing with countless medications and injections? They will all be a thing of the past!"

CelluFend and Insufend, word for word

MedlinePlus lists not taking "your medicines correctly" among the causes of hyperglycemia.

"This Diabetes Breakthrough Candy Takes You Off Your T2D Meds" (page title)

GlucoTrust Bites

NIDDK: "Take your medicines as they were prescribed, even if you feel good or have reached your blood glucose, blood pressure, or cholesterol goals."

Sales pages read on September 25 and 27, 2026 (see each review). CDC, "Diabetic Ketoacidosis" (May 15, 2024); NIDDK, "Managing Diabetes" (October 2023); MedlinePlus, "Hyperglycemia" (May 10, 2024). Read on September 27, 2026. Herbs and medicines can also interact in the other direction: NCCIH describes a study in healthy adults where taking goldenseal extract with metformin lowered metformin levels about 25 percent, a drop "enough to potentially hinder glucose control in people with type 2 diabetes taking metformin."

## Frequently asked questions

**My blood sugar is over 300. What should I do?**

If it stays at 300 mg/dL or above, the CDC says to go to the emergency room or call 911 right away. Same if your breath smells fruity, you're vomiting and can't keep anything down, you're having trouble breathing, or you have multiple signs and symptoms of DKA.

**What are the symptoms of high blood sugar?**

Feeling thirsty, tired or weak, headaches, urinating often and blurred vision, according to MedlinePlus. Many people with type 2 diabetes or prediabetes have no symptoms at all.

**What blood sugar level is too high?**

With diabetes, the NIDDK says above 180 mg/dL for most people. On a lab test, the CDC counts a fasting level of 126 mg/dL or above as the diabetes range, and a random test of 200 mg/dL or above counts too; the NIDDK says the random test is used when there are symptoms. The emergency line is a reading that stays at 300 mg/dL or above.

**Can you have high blood sugar without diabetes?**

Less commonly, yes. MedlinePlus names pancreas or adrenal problems, certain medicines and severe illnesses. A high reading from a pharmacy or health fair is worth taking to your doctor, who may re-test you, the CDC says.

**Can a supplement bring high blood sugar down?**

NCCIH says "for most supplements, there isn't evidence to support a beneficial effect on diabetes or its complications," and calls it "very important not to replace medical treatment for diabetes with an unproven health product or practice."

## Related pages

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### [Low blood sugar (hypoglycemia): what to do in the first 15 minutes](https://glucosebench.com/low-blood-sugar)

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Updated September 27, 2026. [See our full method](https://glucosebench.com/how-we-choose)

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